Product Information |
Product name |
Urolithin A / 3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one |
CAS No. |
1143-70-0 |
Molecular Formula |
C13H8O4 |
Molecular Weight |
228.2 |
Quality Standard |
98% up by HPLC |
Appearance |
White powder |
COA of Urolithin A |
ITEMS |
SPECIFICATION |
RESULT |
Appearance |
White to beige fine powder |
Conforms |
Identification |
Positive |
Conforms |
Loss on drying |
≤ 1.0% |
0.37% |
Heavy metal |
As ≤ 1.0 ppm Pb ≤ 2.0 ppm Cd ≤ 2.0 ppm Hg ≤ 1.0 ppm |
Conforms Conforms Conforms Not detected |
Microbiological test |
Total plate count ≤ 10000 cfu/g Yeast & Mold ≤ 300 cfu/g E. Coli Negative Salmonella Negative Staphylococcus aureus Negative |
Conforms Conforms Negative Negative Negative |
Assay |
≥ 98% |
99.13% |
Conclusion |
Conforms with specification |
Usage |
Urolithin A is produced by the gut flora and is a natural metabolite of ellagitannins, a class of compounds found in pomegranates and some other fruits and nuts.
Function of Urolithin A
How does Urolithin A work? Ellagic
acids and Ellagitannins are Urolithin A precursors.
Ellagitannins are hydrolyzed from the intestine into release Ellagic acid, and
this is processed from the gut microflora to urolithins through the increasing
loss in 1 of its two lactones successive removal of hydroxyl groups. Once It’s
consumed in the intestines, then Urolithin A powder enters the flow System of
this intestine.
Mitophagy, according to Wikipedia definition, is the selective degradation of
your mitochondria by autophagy. It often occurs to defective mitochondria
following damage or stress. However, as we age, Mitophagy function becomes less
efficient. Luckily,Urolithin A is approved to stimulate mitophagy in a
conserved manner across different species.
Human clinical trials show that
Urolithin A supplementation is especially beneficial to anti-aging and muscular
strength improvement. It may slow down a part of the aging process that’s
related to the creation of energy within our cells.
Muscle wellness undergoes a natural drop when you are 30+. Skeletal muscle mass
declines along with a reduction in strength. Urolithin A enhances adrenal and
muscular function, supplying more energy. It’s a naturally-occurring anti-aging
chemical that may benefit anyone seeking to maintain muscle health.
500mg Urolithin A was proven to cause gene expression linked to mitochondrial
metabolism and function and boost the potency of the hamstring leg muscle in
steps of knee extension and flexion in obese 40 to 65-year-olds. Information
from two randomized double-blind human clinical trials.