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S-Adenosyl-L-methionine Disulfate Tosylate/ SAMe 97540-22-2

S-Adenosyl-L-methionine Disulfate Tosylate/ SAMe 97540-22-2

95%-103% up by HPLC, USP43
  • Product Details

Product Information


Product name

S-Adenosyl-L-methionine Disulfate Tosylate/ SAMe

Ademetionine disulfate tosylate

CAS No.

97540-22-2

Molecular Formula

C15H22N6O5S.2(H2SO4).C7H8SO3

Molecular Weight

766,79

Quality Standard

95%-103% by HPLC, USP43

Appearance

White to off-white powder


COA

ANALYSIS

SPECIFICATION

RESULTS

Appearance

White to off-white Powder

White to off-white Powder

Identification:

Infrared

Conforms to the Reference Spectrum

Complied

HPLC

The retention time of the major peak corresponds to the reference sample

Complied


Water Content(K.F)

3.0% MAX

1.2%

Sulphated Ash

0.5% MAX.

0.3%

PH (5% AQUEOUS SOLUTION)

1.0 -2.0

1.2

S, S-Isomer (HPLC)

75.0% MIN

82.4%

SAM-e ION (HPLC)

49.5 - 54.7%

51.5%

P-Toluenesulfonic Acid

21.0%–24.0%

22.5%

Content of Sulfate (SO4) (HPLC)

23.5%–26.5%

25.0%

S-Adenosyl-L-methionine Disulfate Tosylate 95.0%–103%

95.0%-103.0%

99.0%

Related substances(HPLC):

-S-ADENOSYL-L-HOMOCYSTEINE

1.0% MAX.

0.17%

- ADENINE

1.0% MAX.

0.26%

- METHYLTHIOADENOSINE

1.5% MAX

0.17%

- ADENOSINE

1.0% MAX.

0.07%

- TOTAL IMPURITIES

3.5% MAX.

1.1%

Heavy Metals

Not more than 10 ppm

Complied

LEAD

Not more than 3 ppm

Complied

CADMIUM

Not more than 1 ppm

Complied

MERCURY

Not more than 0.1 ppm

Complied

ARSENIC

Not more than 2 ppm

Complied

Micorbiology:

Total Aerobic Count

≤1000cfu/g

Complies

Yeast and mold count

≤100cfu/g

Complies

Microbiology E. coli

Absent/10g

Complies

S. aureus

Absent/10g

Complies

Salmonella

Absent/10g

Complies

Conclusion

Complies with USP43


Usage


S-Adenosyl-L-methionine Disulfate Tosylate has a wide range of applications due to its unique biological properties.

1. As a Food Supplement

    S-Adenosyl-L-methionine Disulfate Tosylate is a form of S-adenosyl-L-methionine (SAMe), which is a naturally occurring compound found in the body. It serves as a methyl donor in biochemical reactions and is involved in various metabolic processes. As a dietary supplement, it is used to support liver health, improve mood and cognitive function, and reduce pain and inflammation associated with osteoarthritis.

2. Antidepressant

    Clinical studies have shown that S-adenosyl-L-methionine (SAMe) has antidepressant effects. It works by increasing the levels of neurotransmitters such as serotonin and dopamine in the brain, which are involved in regulating mood and emotional responses. S-Adenosyl-L-methionine Disulfate Tosylate, as a stable form of SAMe, can be used as an alternative treatment for depression, especially in cases where traditional antidepressants are not effective or cause side effects.

3. Research in Liver Disease and Osteoarthritis

    S-Adenosyl-L-methionine has been extensively studied in the context of liver disease and osteoarthritis. In liver disease, it has been shown to improve liver function and reduce liver damage caused by various factors such as alcohol, drugs, and viruses. In osteoarthritis, it has been found to reduce pain and inflammation, and improve joint function. S-Adenosyl-L-methionine Disulfate Tosylate, as a stable and effective form of SAMe, can be used in research to further explore its potential therapeutic effects in these areas.

4. Other Potential Uses

    In addition to the above-mentioned uses, S-Adenosyl-L-methionine Disulfate Tosylate may also have other potential applications. For example, it may be used to support cognitive function and reduce the risk of neurodegenerative diseases such as Alzheimer's disease. However, more research is needed to confirm these potential uses and their efficacy.


Sinoway’s advantage:


The production of S-Adenosyl-L-methionine Disulfate Tosylate in China uses a unique enzymatic engineering innovation platform, which has overcome several technical challenges in the enzymatic synthesis of adenosine methionine. Successfully, a novel production technology for adenosine methionine using solid-phase enzymatic synthesis has been developed, and patents have been successfully applied for in China, the United States, and the European Union. Compared to the current most advanced fermentation production technology globally, this novel solid-phase enzymatic synthesis process and technology for producing adenosine methionine offers significant investment and competitive advantages, including low energy consumption, low pollution, lower investment costs, higher quality, and lower production costs.



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