Nicotinamide Riboside Chloride/ NRcl 23111-00-4

98% up by HPLC

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Product Information

Product name	Nicotinamide Riboside Chloride; NR Chloride; NRCL; NR-CL
CAS No.	23111-00-4
Molecular Formula	C11H15ClN2O5
Molecular Weight	290.70
Quality Standard	98% up by HPLC
Appearance	White to light yellow powder

COA

ANALYSIS	SPECIFICATION	RESULTS
Appearance	White to light yellow powder	Conforms
Water (by KF)	≤0.5%	0.18%
Solubility	Colorless liquid	Conforms
Related substances (by HPLC)	Nicotinamide ≤2.0%	0.10%
	Methyl acetate ≤0.5%	0.02%
	Nicotinamide riboside triacetate ≤0.5%	ND
	Ribofuranose tetraacetate ≤0.5%	ND
	Acetamide ≤0.5%	ND
Total impurities(by HPLC)	≤2.0%	0.78%
Ethanol(by GC)	≤1.0%	0.002%
Methanol	≤3000ppm	Conforms
Acetone	≤5000ppm	Conforms
Heavy metal contents	<10ppm	Conforms
Pb	≤0.5ppm	Conforms
As	≤0.5ppm	Conforms
Hg	≤0.1ppm	Conforms
Cd	≤1ppm	Conforms
E.coli	Not detected	ND
Mold and yeast	≤50 CFU/g	Conforms
Salmonella	Not detected	Conforms
Total microbial count	≤750 CFU/g	Conforms
Loss on drying	≤2.0%	0.0811%
Ignition residue	≤0.1%	0.02%
Bulk density	0.60g/ml – 0.65g/ml	Conforms
Content(by HPLC)	≥98%	99.12%
Purity(by HPLC)	≥98%	99.22%
Conclusion	The sample complies with the above Specifications.

Usage

Nicotinamide Riboside Chloride, also known as NR Chloride(NR-CL), is a chloride salt form of nicotinamide ribose (NR). It serves as a precursor to NAD+ (nicotinamide adenine dinucleotide), a coenzyme found in all living cells that is crucial for energy metabolism and many other biochemical reactions.

The primary function of Nicotinamide Riboside Chloride is to increase the levels of NAD+ in the body. By boosting NAD+ levels, it activates SIRT1 and SIRT3, which are sirtuin proteins that play a role in regulating metabolism, inflammation, and aging. Increased NAD+ levels and SIRT activation have been shown to enhance oxidative metabolism, protect against high-fat diet-induced obesity, and reduce cognitive deterioration in transgenic mouse models of Alzheimer's disease.

Nicotinamide Riboside Chloride is also used in dietary supplements and foods as a source of vitamin B3 (niacin). It has good water solubility and stability, making it a suitable ingredient for various applications. However, it should be noted that Nicotinamide Riboside Chloride is intended for research purposes and should not be used for personal consumption.

Highlight of Sinoway’s Nicotinamide Riboside Chloride(NRCL)

√ Stable quality, no purity degrade problems.

√ Large production capacity 5tons each month.