Product Information |
Product name |
Nicotinamide Riboside Chloride; NR Chloride; NRCL; NR-CL |
CAS No. |
23111-00-4 |
Molecular Formula |
C11H15ClN2O5 |
Molecular Weight |
290.70 |
Quality Standard |
98% up by HPLC |
Appearance |
White to light yellow powder |
COA |
ANALYSIS |
SPECIFICATION |
RESULTS |
Appearance |
White to light yellow powder |
Conforms |
Water (by KF) |
≤0.5% |
0.18% |
Solubility |
Colorless liquid |
Conforms |
Related substances (by HPLC) |
Nicotinamide ≤2.0% |
0.10% |
Methyl acetate ≤0.5% |
0.02% |
|
Nicotinamide riboside triacetate ≤0.5% |
ND |
|
Ribofuranose tetraacetate ≤0.5% |
ND |
|
Acetamide ≤0.5% |
ND |
|
Total impurities(by HPLC) |
≤2.0% |
0.78% |
Ethanol(by GC) |
≤1.0% |
0.002% |
Methanol |
≤3000ppm |
Conforms |
Acetone |
≤5000ppm |
Conforms |
Heavy metal contents |
<10ppm |
Conforms |
Pb |
≤0.5ppm |
Conforms |
As |
≤0.5ppm |
Conforms |
Hg |
≤0.1ppm |
Conforms |
Cd |
≤1ppm |
Conforms |
E.coli |
Not detected |
ND |
Mold and yeast |
≤50 CFU/g |
Conforms |
Salmonella |
Not detected |
Conforms |
Total microbial count |
≤750 CFU/g |
Conforms |
Loss on drying |
≤2.0% |
0.0811% |
Ignition residue |
≤0.1% |
0.02% |
Bulk density |
0.60g/ml – 0.65g/ml |
Conforms |
Content(by HPLC) |
≥98% |
99.12% |
Purity(by HPLC) |
≥98% |
99.22% |
Conclusion |
The sample complies with the above Specifications. |
Usage |
Nicotinamide Riboside Chloride, also known as NR Chloride(NR-CL), is a chloride salt form of nicotinamide ribose (NR). It serves as a precursor to NAD+ (nicotinamide adenine dinucleotide), a coenzyme found in all living cells that is crucial for energy metabolism and many other biochemical reactions.
The primary function of Nicotinamide Riboside Chloride is to increase the levels of NAD+ in the body. By boosting NAD+ levels, it activates SIRT1 and SIRT3, which are sirtuin proteins that play a role in regulating metabolism, inflammation, and aging. Increased NAD+ levels and SIRT activation have been shown to enhance oxidative metabolism, protect against high-fat diet-induced obesity, and reduce cognitive deterioration in transgenic mouse models of Alzheimer's disease.
Nicotinamide Riboside Chloride is also used in dietary supplements and foods as a source of vitamin B3 (niacin). It has good water solubility and stability, making it a suitable ingredient for various applications. However, it should be noted that Nicotinamide Riboside Chloride is intended for research purposes and should not be used for personal consumption.
Highlight of Sinoway’s Nicotinamide Riboside Chloride(NRCL)
√ Stable quality, no purity degrade problems.
√ Large production capacity 5tons each month.