Vitamin A acid / Tretinoin / Retinoic Acid 302-79-4

99% up, Cosmetic Grade

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Product Information

Product name	Vitamin A acid / Tretinoin / Retinoic Acid
CAS No.	302-79-4
Molecular Formula	C20H28O2
Molecular Weight	4300.44
Quality Standard	99% up, Cosmetic Grade
Appearance	Light yellow powder

COA of Vitamin A acid / Tretinoin / Retinoic Acid

Items	Specification	Results
Appearance	Yellow Powder	Complies
Odor	Characteristic	Complies
Sieve analysis	100% pass 80mesh	Complies
Heavy Metal	< 10ppm	Complies
Ash	≤1.0%	0.22%
Pb	≤2.0ppm	Not Detected
As	≤0.1pm	Not Detected
Cd	≤0.3ppm	Not Detected
Residual Solvents	≤100ppm	Complies
Residual Pesticide	Negative	Complies
Total Plate Count	≤1,000cfu/g	Complies
Mold and Yeast	≤100cfu/g	Complies
E.Coli	Negative	Negative
Salmonella	Negative	Negative
Related substance (HPLC)	98% min	99.8%
Assay	98%	98.22%
Conclusion	Complies with In-house standard

Usage

Retinoic acid (is also called Vitamin A acid / Tretinoin /) is a metabolite of vitamin A and plays an important role in cell growth, differentiation and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptor α/β/γ The IC50 is 14 nm. Retinoic acid and PPAR β/δ The combined Kd value is 17 nm. Retinoic acid can inhibit transcription factor Nrf2 by activating retinoic acid receptor.

Function of Retinoic Acid
1. Retinoic acid is the acid form of vitamin a and so also known as all-trans retinoic acid or atra.

2. Retinoic acid is a drug commonly used to treat acne vulgaris and keratosis pilaris.

3. Retinoic acid is available as a cream or gel.retinoic acid is also used to treat acute promyelocytic leukemia.

4. Retinoic acid can stimulate skin growth and keep epidermic normal.

5. Retinoic acid can slow down skin aging process for solarization, remove tiny wrinkles, and retinoic acid canreduce skin roughness, so skin will become ruddy.