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Ciclopirox Olamine 41621-49-2

Ciclopirox Olamine 41621-49-2

97.5% up by HPLC; CEP/USP
  • Product Details

Product Information

 

Product name

Ciclopirox Olamine;

Ciclopirox ethanolamine; HOE296

CAS No.

41621-49-2

Molecular Formula

C12H17NO2.C2H7NO

Molecular Weight

268.356

Quality Standard

97.5% up by HPLC/ CEP/ USP

Appearance

White crystalline powder

 

COA

ANALYSIS

SPECIFICATION

RESULTS

Appearance

White crystalline powder

Conforms

Identification(IR)

Similar to reference standard

Conforms

Ciclopirox Olamine content

97.5% - 101.5%

99.75%

Ethanolamine content

223-230mg/g

225mg/g

Residue on ignition

0.1%

0.05%

Loss on drying

1.5%

0.35%

Heavy metals

10 ppm

Conforms

pH

8.0-9.0

8.4

Related substances

Impurity A<0.5%

Total impurities<0.5%

Single impurities<0.1%

Conforms

Solubility

Soluble in alcohol and organic solvents such as dichloromethane and slightly in water

Conforms

Residual solvents

dichloromethane600ppm

toluene890ppm

ethyl5000ppm

dichloromethane250ppm

toluene280ppm

ethyl1200ppm

Conclusion

The sample complies with the Requirements of USP34.

 

Usage

 

Function of Ciclopirox Olamine

Ciclopirox Olamine, also known as Ciclopirox, exhibits the following functionalities:

 

1. Broad-spectrum Antifungal Activity: Ciclopirox is a synthetic antifungal agent with oral activity that inhibits a wide range of dermal fungi, yeasts, molds, and many pathogenic Gram-positive and Gram-negative bacteria. It effectively suppresses the growth of dermal fungi and yeasts at concentrations of 4-8 micrograms per milliliter. It is particularly suitable for the treatment of skin infections caused by dermatophytes, Candida species, and other fungi, such as hand, foot, onychomycosis, tinea corporis, and tinea cruris.

2. Anticancer and Anti-inflammatory Effects: Studies have shown that Ciclopirox also possesses anticancer and anti-inflammatory properties, inhibiting cell proliferation and inflammatory responses to a certain extent. However, further research and validation are required for the application of these properties in medical practice.

 

Advantages in China

1. Independent Research and Development: Ciclopirox is an antifungal drug developed by the Hubei Pharmaceutical Industry Research Institute in China, reflecting China's independent innovation capabilities in antifungal drug research and development.

2. Large-scale Production: With advancements in domestic pharmaceutical technology and cost control, China has the capacity to produce Ciclopirox on a large scale. This not only meets domestic market demand but also helps reduce drug prices, improving patient access to medication.

3. Quality Control: Chinese pharmaceutical companies strictly adhere to the quality standards and production process requirements set by the National Medical Products Administration (NMPA) during production, ensuring the quality and safety of drugs such as Ciclopirox.

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If you are interested in our products and want to know more details,please leave a message here,we will reply you as soon as we can.

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