Product Information |
Product name |
Troxerutin |
CAS No. |
7085-55-4 |
Molecular Formula |
C33H42O19 |
Molecular Weight |
742.685 |
Quality Standard |
95% up |
Appearance |
Yellowish-green, crystalline powder |
COA
|
ANALYSIS |
SPECIFICATION |
RESULTS |
Appearance |
Yellowish-green, crystalline powder |
Yellowish-green, crystalline powder |
Identification |
The infrared absorption pattern should be consistent with reference product |
Conforms |
The principal peak in the chromatogram obtained with the test solution is similar to the chromatogram obtained with the reference solution (a) |
Conforms |
|
Related substance |
Purity of main peak ≥ 80.0% |
89.5% |
2.7% |
||
Other single component peak ≤ 5.0% |
2.1% |
|
Ethylene oxide |
≤ 1ppm |
Not detected |
Methanol |
≤ 3000ppm |
410ppm |
Loss on drying |
≤5.0% |
0.68% |
Sulphated ash |
≤0.4% |
0.07% |
Assay |
95.0% - 105.0% |
100.8% |
Microbial Limit |
45cfu/g |
|
TYMC≤100cfu/g |
<10cfu/g |
|
Escherichia coli: Not detected in 1g |
Not detected |
|
Conclusion |
The sample complies with the Ph.Eur.11.2. |
Usage |
Troxerutin, also known as rutin derivative or venoruton, is a bioflavonoid compound derived from natural sources such as the Japanese pagoda tree, sophora japonica, and other plants. It is a yellowish-white crystalline powder that is highly soluble in water.
Pharmacological Effects
1. Anti-inflammatory Properties: Troxerutin has been shown to reduce the production of inflammatory
2. Antioxidant Properties: It acts as a powerful antioxidant by neutralizing free radicals, thus protecting cells and tissues from oxidative stress and damage.
3. Anti-cancer Properties: Troxerutin has demonstrated anti-cancer activity by inhibiting the growth and spread of cancer cells, and protecting healthy cells from damage caused by cancer treatments like chemotherapy and radiation therapy.
4. Vascular Effects: It helps to improve blood flow, reduce the risk of blood clots, and exhibits anti-thrombotic properties. Troxerutin also has a weak vasoconstrictive effect, reducing capillary permeability and fragility, thereby preventing edema caused by increased vascular permeability.