|
Product Information |
|
Product name |
tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate; Rosuvastatin Intermediate R1 |
|
CAS No. |
289042-12-2 |
|
Molecular Formula |
C29H40FN3O6S |
|
Molecular Weight |
116.3 |
|
Quality Standard |
99% up by HPLC, Single impurity < 0.3%, total impurities < 0.5% |
|
Appearance |
White to off-white powder |
|
COA |
|
ANALYSIS |
SPECIFICATION |
RESULTS |
|
Appearance |
White to off-white powder |
White powder |
|
Identification(by HPLC) |
The retention time of the sample peak should correspond to that of standard. |
Conforms |
|
Loss on drying |
≤1.0% |
0.09% |
|
Related substances |
·Isomer ≤0.1% |
0.01% |
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·Any single impurity ≤0.3% |
0.08% |
|
|
·Total impurities ≤0.5% |
0.09% |
|
|
Purity |
≥ 99.0% |
99.91% |
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Conclusion |
The sample complies with the Requirements of In House Specifications. |
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Synthetic route of Rosuvastatin calcium |
Rosuvastatin Intermediate R1 (CAS No.: 289042-12-2) is one of key intermediates of rosuvastatin calcium.
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