(R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine dihydrochloride Ibrutinib intermediate 1701403-10-2

Molecular Structure:

Synonyms:  R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine dihydrochloride

Function of Ibrutinib

Ibrutinib is a chemotherapeutic agent, which is mainly used for mantle cell lymphoma, chronic lymphocytic leukemia, small lymphocytic lymphoma and Waldenstrom's macroglobulinemia. It can also be used for diseases such as B-cell malignancies. The drug is a small molecule BTK inhibitor that can inhibit the proliferation and survival of malignant B cells in vivo, as well as cell migration and substrate adhesion in vitro. It cannot be taken with grapefruit juice during the use of the drug, otherwise it will cause the drug Absorb more. At the same time, the drug also has certain side effects, which may cause bleeding in patients, increase the chance of infection, decrease blood cells, interstitial lung disease, arrhythmia, hypertension, and secondary malignant tumors. At the same time, pregnant women are not recommended to take the drug, because the drug may damage the fetus, and the drug may also cause skeletal muscle pain and joint pain.