Betamethasone 17,21-dipropionate 5593-20-4

USP43

Product categories

New Products

Product Details

Product Information

Product name	Betamethasone 17,21-dipropionate； Betamethasone dipropionate； BDP
CAS No.	5593-20-4
Molecular Formula	C28H37FO7
Molecular Weight	504.596
Quality Standard	97.0% - 103.0%
Appearance	White to cream white,odorless powder

COA

Test Items	Specifications	Results
Appearance	White to cream white, odorless powder	White odorless powder
Solubility	Very soluble in chloroform,freely soluble in acetone and in alcohol; very slightly soluble in water.	Conforms
Identification	IR Complies with the standard	Conforms
Specific rotation	+88°to +94°	+90.7°
Loss on drying	≤ 0.5%	0.07%
Residue on ignition	≤ 0.1%	0.06%
Assay(HPLC)	97.0% - 103.0%	99.8%
Chromatographic purity by HPLC
- Any impurity	≤ 1.0%	0.26%
-Total impurities	≤ 2.0%	0.44%
Residual Solvents(GC)
Dichloromethane	≤ 600ppm	Conforms
Ethyl acetate	≤ 5000ppm	Conforms
Methanol	≤ 3000ppm	Conforms
Tetrahydrofuran	≤ 720ppm	Conforms
Pyridine	≤ 200ppm	Conforms
Conclusion	The product complies with the specification of USP43

Usage

Core Functions of Betamethasone 17,21-Dipropionate

Betamethasone 17,21-dipropionate (BDP) is a potent synthetic topical corticosteroid widely used in dermatology for its anti-inflammatory and anti-pruritic properties. As a key pharmaceutical intermediate, it is formulated into creams, ointments, and lotions to treat chronic skin conditions such as eczema, psoriasis, and dermatitis. BDP works by inhibiting inflammatory mediators, reducing redness, swelling, and itching, making it a cornerstone in dermatology APIs. Its high efficacy and rapid absorption also make it suitable for custom synthesis in specialized drug delivery systems.

Sinoway’s Advantages:

We Sinoway, stands out as reliable API suppliers, cooperates closely with Chinese factories with advanced manufacturing facilities and production technologies. With decades of expertise in steroid synthesis, these factories ensure high-purity BDP (≥99.5%) compliant with international pharmacopeia standards (liked USP). Cost efficiency is another key strength -- competitive pricing for bulk supply, attracting global pharmaceutical companies. Additionally, we Sinoway offers custom synthesis services to meet specific formulation requirements, backed by robust R&D capabilities and fast delivery timelines. Strict quality control, coupled with certifications like ISO9001, reinforces our position as trusted partners in the global anti-inflammatory drugs market.