The Difference Between Reduced Glutathione And Oxidized Glutathione-www.china-sinoway.com

The difference between reduced glutathione and oxidized glutathione

Sep 19, 2022

Glutathione has two forms, reduced form (GSH) and oxidized form (GSSG). Reduced glutathione (GSH) is the main active state, accounting for about 95%; oxidized glutathione (GSSG) is the inactive state, accounting for about 1%.

The difference between reduced glutathione and oxidized glutathione are: different molecular formulas, different melting points, and different uses.

1. Different molecular formulas
Reduced glutathione: molecular formula is C10H17N3O6S, molecular weight is 307.33
Oxidized glutathione: molecular formula is C20H32N6O12S2, molecular weight is 612.63

2. Different melting points
Reduced glutathione: Decomposes at a melting point of 189 to 193 °C.
Oxidized glutathione: Melting point: 178 ℃ decomposition.

3. Different uses
Reduced glutathione: It has a certain curative effect on various liver diseases, especially alcohol poisoning liver disease and drug poisoning liver disease. It has antioxidant, integrated detoxification and other effects. It is used in medicines, nutraceuticals, healthy functional foods, food supplements, beauty cosmetics, etc.
Oxidized glutathione: used as a hydrogen acceptor for scientific research, experiments, and enzymatic determination of NADP and NADPH.

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