Powerful Health Benefits Of Nattokinase In Cardiovascular Field-www.china-sinoway.com

Powerful health benefits of nattokinase in cardiovascular field

Jun 17, 2022

Nattokinase is one of the most active and unique functional components in natto. It is a single compound with potential effects such as antithrombotic, blood pressure, anticoagulation, antiatherosclerosis and neuroprotection.

Nattokinase is a serine protease purified and extracted from natto. Nattokinase not only has fibrinolysis activity, but also can activate other fibrinolytic enzymes, such as pro-urokinase and tissue plasminogen activator. Compared with other fibrinolytic drugs (urokinase, t-PA enzyme, streptokinase), it has the advantages of low side effects, low cost, long half-life, etc., and has the potential as a cardiovascular disease drug and functional food additive.

1. Reduce the formation of blood clots
According to a double-blind, placebo-controlled trial (in 12 healthy young men), oral nattokinase subjects had increased D-dimer concentrations and blood fibrin/fibrinogen degradation products, which were comparable to tissue fibrinogen levels. Compared with the half-life (4-20 minutes) of lysinogen initiator (t-PA) and urokinase in human blood, its effect lasts longer (about 8 hours or more).

2. Prevent atherosclerosis
A randomized controlled trial (26 weeks, the object is 82 patients with hyperlipidemia), divided into two groups, one group was given hypolipidemic drug: simvastatin (simvastatin 20mg), the other group was given nattokinase (daily dose 6000FU). After the test, it was found that the common carotid artery medial intima thickness (CCA-IMT) and the carotid plaque size were decreased in both groups, but the magnitude was more significant in the nattokinase group.

3. Lower blood pressure
A randomized, double-blind, placebo-controlled trial in 86 patients with prehypertension or stage 1 hypertension showed that oral nattokinase (2,000 FU) for 8 weeks reduced blood pressure values compared to placebo.

4. Beneficial for hyperlipidemia
A randomized, double-blind, placebo-controlled, parallel-controlled study (6 months in duration, with 47 patients with hyperlipidemia) divided into 3 groups: nattokinase group, nattokinase combined with red yeast rice Rice extract, placebo. It was found that the effects of the single prescription (nattokinase) on blood lipids did not appear until the 6th month, while the compound prescription (nattokinase combined with red yeast rice extract) improved all blood lipid measures from the first month.

Tags : Natto extract Nattokinase Nattokinase cardiovascular

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