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New function of L-glutathione Reduced: Prevention and treatment of stroke and improvement of Parkinson's symptoms

New function of L-glutathione Reduced: Prevention and treatment of stroke and improvement of Parkinson's symptoms

Nov 16, 2022

Glutathione (L-glutathione reduced/GSH, CAS No.: 70-18-8) is a γ- The tripeptide of amide bond and sulfhydryl group, composed of glutamic acid, cysteine and glycine, exists in almost every cell of the body. Glutathione can help maintain the normal immune system function, and has antioxidant effect, integrated detoxification effect.


1. Prevention of brain degeneration
Glutathione is a major shield for the brain and nervous system. In terms of prevention and treatment of brain diseases, glutathione is a "guard" that protects the brain from oxidative stress and inflammatory damage, and also plays a role in preventing and treating stroke (atherosclerosis). In addition, science has also verified that glutathione can prevent brain degeneration, senile dementia, Parkinson's disease and other neurodegenerative diseases.
Parkinson's disease is a degenerative disease of the central nervous system commonly seen in the elderly aged 60 years or above. The main lesions are in the substantia nigra and striatum pathways. The decrease of dopamine production leads to static tremor, increased muscle tension, and slow movement. Brain cells contain dopamine. When the content of glutathione in dopamine neurons decreases by 40%~50%, Parkinson's disease will occur.

2. Keep dopamine active

Studies on Parkinson's disease and glutathione have shown that intravenous administration of glutathione can help improve the symptoms of Parkinson's disease. The mechanism of glutathione to alleviate Parkinson's disease is not to increase dopamine index, but to keep or more active dopamine in brain cells.
Glutathione can increase the sensitivity of the neurotransmitter serotonin (also known as serotonin), which is the reason why many depressed Parkinson's patients have made significant progress. In some cases, patients have made significant progress after intravenous administration of glutathione IV and gradually reduced their use of Parkinson's drugs
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