Product Information |
Product name |
21-hydroxy-20-methylpregn-4-en-3-one; Bisnoralcohol / BA; Progesterone intermediate; Ursodeoxycholic acid intermediate |
CAS No. |
60966-36-1 |
Molecular Formula |
C22H34O2 |
Molecular Weight |
330.511 |
Purity |
99.0% up by HPLC |
Appearance |
White or almost white crystalline powder |
COA |
ANALYSIS |
SPECIFICATION |
RESULTS |
Appearance |
White or almost white crystalline powder |
White crystalline powder |
Identification |
The retention time of main peak should be consistent with that of work reference |
Conforms |
Loss on drying |
≤0.5% |
0.16% |
Specific rotation |
+90°~ +96°(C=10 Ethyl alcohol) |
+94.6° |
Assay (HPLC) |
≤97.0% on the dried basis |
99.5% |
Related substances(HPLC) |
Impurity DBA ≤0.3% |
0.07% |
Impurity 4AD ≤0.3% |
0.01% |
|
Any single impurity ≤0.5% |
0.07% |
|
Total impurities ≤1,0% |
0.34% |
|
Purity ≥ 99.0% |
99.66% |
|
Residual solvents |
Methanol ≤ 3000 ppm |
NA |
Ethyl acetate ≤ 5000 ppm |
NA |
|
Conclusion |
The sample complies with the Requirements of In Enterprise Specifications. |
Usage |
Applications of 21-hydroxy-20-methylpregn-4-en-3-one (Bisnoralcohol / BA , CAS No. 60966-36-1) as an Intermediate for Progesterone and Ursodeoxycholic Acid
Progesterone, which is a significant steroidal hormone with broad physiological effects such as regulating menstruation, pregnancy support, and promoting embryonic development. As such, this intermediate plays a pivotal role in the pharmaceutical industry. The main functions of ursodeoxycholic acid include: dissolving cholesterol gallstones, promoting bile secretion and excretion, protecting liver function, regulating lipid metabolism, and treating diseases such as bile reflux gastritis. It works by reducing the saturation of cholesterol in bile, promoting the dissolution and excretion of cholesterol, while improving liver function and lipid metabolism, effectively alleviating symptoms of related diseases.