Product Information |
Product name |
Metaraminol Bitartrate |
CAS No. |
33402-03-8 |
Molecular Formula |
C9H13NO2.C4H6O6 |
Molecular Weight |
317.29 |
Molecular Structure |
|
Quality Standard |
99% up by HPLC |
Appearance |
White crystalline powder |
COA |
ANALYSIS |
SPECIFICATION |
RESULTS |
Appearance |
White crystalline powder |
Complies |
Solubility |
Freely soluble in water, sparingly soluble in ethanol(96%); practically insoluble in ether. |
Complies |
Identification |
A. In the test for Related substances the principal spot obtained with solution(2) corresponds to that obtained with solution(4). |
Complies |
B. An intense blue colour is produced. |
Complies |
|
C. A mauve colour is immediately produced in the toluene layer. |
Complies |
|
pH |
3.2-3.5 |
3.35 |
Phenones |
Absorbance at 310nm,not more than 0.2,calculated with reference to the dried substance. |
Complies |
Related substances |
Any impurity ≤0.5% |
Complies |
Loss on drying |
≤0.5% |
0.07% |
Sulphated Ash |
≤0.1% |
0.01% |
Heavy metals |
≤ 20ppm |
Complies |
Sulphated Ash |
≤0.1% |
0.01% |
Micorbial count |
≤ 100cfu/g |
Complies |
Assay (dried substance) |
99.0% - 101.0% |
100.10% |
Conclusion |
The product complies with specification. |
Usage |
What is Metaraminol Bitartrate?
Metaraminol Bitartrate injection is an α1 and α2 adrenergic receptor agonist. Metaraminol Bitartrate also has a certain stimulating effect on the β1 receptor of the heart. It can constrict blood vessels, reflexively slow down the heart rate, and increase the contractility of the myocardium. Metaraminol Bitartrate has certain effects in increasing blood pressure.
Metaraminol Bitartrate injection is used to prevent and treat hypotension caused by sepsis or cardiogenic shock. It can also be used to prevent and treat shock caused by drug allergies or surgical complications, bleeding, brain trauma or brain tumors, etc. Induced hypotension, this drug can be used as an auxiliary symptomatic treatment. It is also suitable for preventing and treating acute hypotension during neuraxial anesthesia.
*Products under the patent are only for R&D use