|
Product Information |
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Product name |
2,4-Dichloropyrimidine； 2,6-Dichloropyrimidine; Pyrimidine, 2,4-dichloro-; Osimertinib intermediate |
|
CAS No. |
3934-20-1 |
|
Molecular Formula |
C4H2Cl2N2 |
|
Molecular Weight |
148.979 |
|
Molecular Structure |
 |
|
Quality Standard |
98% up by HPLC |
|
Appearance |
Pale yellow or off-white powder |
|
COA |
|
ANALYSIS |
SPECIFICATION |
RESULTS |
|
Melting point |
58-60℃ |
58.5-60℃ |
|
Appearance |
Pale yellow or off-white powder |
Conforms |
|
Water |
≤ 0.2% |
0.08% |
|
Residue on ignition |
≤ 0.3% |
0.23% |
|
Assay (by HPLC) |
≥ 98.0% |
99.2% |
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Conclusion |
The product meets enterprise standard CDMO service: We can customized manufacturing according to your requirement. |
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Usage |
What is 2,4-Dichloropyrimidine?
2,4-Dichloropyrimidine is one of key
intermediates of Osimertinib. Osimertinib
is used to treat locally advanced or metastatic non-small-cell lung
cancer (NSCLC), if the cancer cells are positive for the T790M mutation
in the gene coding for EGFR or for activating EGFR mutations.
Sinoway was established in 1987, and is specialized in research, development, custom manufacturing and trading of pharmaceutical APIs, Intermediates, health & food supplements, cosmetic raw materials, herbal extracts, FDFs and custom service all over the world.
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