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Atomoxetine hydrochloride 82248-59-7

Atomoxetine hydrochloride 82248-59-7

99% up by HPLC, GMP
  • Product Details

Product Information


Product name

Atomoxetine hydrochloride; Atomoxetine HCL

Alias

Benzenepropanamine,N-methyl-g-(2-methylphenoxy)-,hydrochloride, (R)-;Benzenepropanamine, N-methyl-g-(2-methylphenoxy)-, hydrochloride, (gR)- (9CI);

CAS No.

82248-59-7

Molecular Formula

C17H22ClNO

Molecular Weight

291.821

Molecular Structure

Quality Standard

99% up by HPLC

Appearance

White crystalline powder


COA


ANALYSIS

SPECIFICATION

RESULTS

Appearance

Off-white or white powder

Conforms

Solubility

It is easy to soluble in absolute ethanol, slightly soluble in water, and almost insoluble in heptane.

Conforms

Melting point

166C ~ 169C

167.5C-168C

Specific rotation

-34.0~ -38

Conforms

Identification

Retention time of the main peak of the test product and the main peak of the reference product are the same

Conforms

The infrared light absorption spectrum should be consistent with the reference spectrum.

Conforms

Identification of chlorides in aqueous solution of this product

Positive

Related substances

O-cresol0.10%

Conforms

Amphetamine0.10%

N.D.

Phenylpropanolamine0.10%

N.D.

Dimethy tomoxetine0.10%

N.D.

Desmethoxetine0.3%

0.03%

The single impurity0.10%

0.04%

The total impurities0.50%

0.14%

Enantiomer

0.15%

0.001%

M-tomoxetine

0.10%

N.D.

P-tomoxetine

0.10%

N.D.

Residual solvents

Methanol0.30%

0.18%

Dichloromethane0.06%

N.D.

N-hexane0.029%

N.D.

Ethyl acetate0.50%

N.D.

Cyclohexane0.388%

N.D.

Toluene0.089%

N.D.

Loss on drying

0.50%

0.09%

Residue on ignition

0.10%

0.04%

Heavy metal

10ppm

Conforms

Assay(drying)

98.0% - 102.0%

99.5%

Conclusion

The product meets enterprise standard.


Usage


What is Atomoxetine hydrochloride?


Atomoxetine hydrochloride (Atomoxetine HCL) is a medication that is primarily used to treat attention deficit hyperactivity disorder (ADHD) in children, adolescents, and adults. Atomoxetine hydrochloride belongs to a class of drugs known as selective norepinephrine reuptake inhibitors (SNRIs). Unlike other medications used to treat ADHD, atomoxetine does not belong to the stimulant class. Instead, it works by increasing the levels of norepinephrine, a neurotransmitter involved in regulating attention, in the brain. By affecting the balance of neurotransmitters, atomoxetine helps to improve attention, reduce impulsivity, and decrease hyperactivity in individuals with ADHD. It is believed to have a longer-lasting effect than stimulant medications and does not carry the risk of abuse or dependence.


*Products under the patent are only for R&D use

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