|
Product Information |
|
Product name |
Dapagliflozin |
|
CAS No. |
461432-26-8 |
|
Molecular Formula |
C21H25ClO6 |
|
Molecular Weight |
408.879 |
|
Quality Standard |
98% up by HPLC |
|
Appearance |
White to pale yellow powder |
|
COA of Dapagliflozin |
|
ITEMS |
SPECIFICATION |
RESULT |
|
Appearance |
White to pale yellow powder |
Conforms |
|
Related substance |
Purity(HPLC) ≥ 99.0% |
99.8% |
|
Single impurity ≤ 0.5% |
0.08% max |
|
|
Total impurity ≤ 1.0% |
0.2% |
|
|
Water |
≤ 3.0% |
1.5% |
|
Conclusion |
The sample meets the standard requirements |
|
|
Usage |
Dapagliflozin is a new type of antidiabetic drug, a sodium-glucose cotransporter 2 inhibitor, and the first SGLT2 inhibitor approved for the treatment of type 2 diabetes. Important choice for improving glycemic control as an adjunct to diet and exercise in adults with type 2 diabetes.
*Products under the patent are only for R&D use
Key Intermediates of Dapagliflozin:
(1) 5-Bromo-2-chlorobenzoic acid
CAS No.: 21739-92-4
(2) D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)Methyl]phenyl]-, tetraacetate, (1S)-
CAS No.: 461432-25-7
(3) 5-bromo-2-chloro-4'-ethoxydiphenylmethane
CAS No.: 461432-23-5
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