Rosuvastatin Calcium 147098-20-2

97% up by HPLC, GMP, DMF, CEP, EP

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Product Details

Product Information

Product name	Rosuvastatin Calcium
CAS No.	147098-20-2
Molecular Formula	C44H54CaF2N6O12S2
Molecular Weight	1001.14
Quality Standard	97% up by HPLC, GMP,DMF,CEP, EP
Appearance	White or almost white powder

COA of Rosuvastatin calcium

ITEMS	SPECIFICATION	RESULT
Appearance	White or almost white hygroscopic powder	Conforms
Identity	IR: Similar to Reference Substance	Conforms
	Enantiomeric purity	Conforms
	It gives reaction (b) of calcium	Positive reaction
Related substance	Impurity A ≤ 0.2% Impurity B ≤ 0.5% Impurity C ≤ 0.8% Unknown impurity ≤ 0.1% Total impurity ≤ 1.2%	Undetected Undetected Undetected Undetected Undetected
Enantiomer	Impurity G ≤ 0.10%	Undetected
Water	≤ 0.60%	1.2%
Assay	97.0～102.0%(anhydrous substance )	99.9%
Conclusion	The results above meet all requirements under EP8.4

Usage

Function of Rosuvastatin calcium

Rosuvastatin calcium is an anti-hyperlipidemia drug which belongs to the inhibitor of HMG-CoA reductase successfully. It is suitable for the treatment of various lipid abnormalities, including hypercholesterolemia, mixed lipid qualitative abnormalities and simple hypertriglyceridemia. Rosuvastatin calcium is listed as the strongest and the most comprehensive statins drugs which has entered into market for lipid-lowering and adjustment. Compared with atorvastatin which is currently recognized with the world's best efficacy, it has a better effect of lowering the level of LDL cholesterol and increasing the level of high-density lipoprotein. Moreover, it has a better tolerance, lower side effects and unique pharmacokinetic characteristics with the half-life about 20h. It only needs to be taken once a day.

*Products under the patent are only for R&D use