Lubiprostone 333963-40-9

99% up by HPLC，for R&D use only

Product categories

New Products

Product Details

Product Information

Product name	Lubiprostone
CAS No.	333963-40-9
Molecular Formula	C20H32F2O5
Molecular Weight	390.46
Molecular Structure
Quality Standard	99% up by HPLC, for R&D use only
Appearance	White powder

COA of Lubiprostone

Items	Standards	Results
Appearance	White crystals or crystalline powder, odorless	Complies
Identification	By IR	Complies
Identification	By HPLC	Complies
Water Content	≤ 0.50%	0.22%
Heavy Metals	≤ 10ppm	Complies
Residual Solvent	n-Hexane: ≤ 290ppm	ND
Residual Solvent	Ethyl acetate: ≤ 5000ppm	0.12%
Related Substances	Total impurities: ≤1.00%	0.04%
Purity(HPLC)	≥ 99.0%	99.96%
Reference Standard	In-house Standard
Conclusion	The product complied to In-house standard.

Usage

Function of Lubiprostone

Lubiprostone is a limited chloride channel activator, which can selectively activate the type 2 chloride channel (CIC-2) located on the luminal cell membrane of the epithelial tip of the gastrointestinal tract to increase the secretion of intestinal juice and intestinal motility, thereby Increase bowel movements, reduce the symptoms of chronic idiopathic constipation, and do not change the concentration of sodium and potassium in the plasma.

Application of Lubiprostone

Adult chronic idiopathic constipation, constipation-type irritable bowel syndrome (only for female patients over 18 years old);