Zidovudine 30516-87-1

99% up by HPLC, USP, EP

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Product Details

Product Information

Product name	Zidovudine
CAS No.	30516-87-1
Molecular Formula	C10H13N5O5
Molecular Weight	283.24
Quality Standard	99% up, USP,EP
Appearance	White powder

COA of Zidovudine

TEST	STANDARD	RESULT
Appearance:	White powder	Complies
Loss on drying	≤ 6.0%	3.83%
Heavy metals	< 10ppm	Complies
As	≤ 3.0 ppm	Complies
Pb	≤ 3.0 ppm	Complies
Cd	≤ 0.5 ppm	Complies
Microbiology
Total plate count	< 1000 cfu/g	326 cfu/g
Yeast & Mold	< 100 cfu/g	28 cfu/g
E. Coli	Negative	Complies
S. Aureus	Negative	Complies
Salmonella	Negative	Complies
Assay	995-101%	99,。5%
Conclusion	Conforms with USP standard

Usage

Function of Zidovudine

Zidovudine is an antiviral drug used in the treatment of patients with AIDS or AIDS-related syndromes and immunodeficiency virus (HIV) infection. It is highly active against retroviruses including human immunodeficiency virus (HIV) in vitro. In virus-infected cells, it is phosphorylated by cellular thymidine kinase to zidovudine triphosphate, which can selectively inhibit HIV reverse transcriptase, leading to the termination of HIV chain synthesis and preventing HIV replication. On March 19, 1987, the US Food and Drug Administration approved the drug for marketing. Zidovudine is the world's first anti-AIDS drug approved by the US FDA.